Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF.
Ma C, et al.
Science. 2018 May 25;360(6391):eaan5931. doi: 10.1126/science.aan5931.
Science. 2018.
PMID: 29798856
Free PMC article.
Primary liver tumors and liver metastasis currently represent the leading cause of cancer-related death. ...In vivo functional studies showed that NKT cells mediated liver-selective tumor inhibition. NKT cell accumulation was regulated by CXCL16 expression of liver …
Primary liver tumors and liver metastasis currently represent the leading cause of cancer-related death. ...In vivo functional studie …